Heparin induces the expression of hepatic triglyceride lipase in a human hepatoma (HepG2) cell line.


Hepatic triglyceride lipase (H-TGL) is a key lipolytic enzyme in the metabolism of human plasma high density lipoproteins. The enzyme is bound to glycosaminoglycans on endothelial cells in the liver and is immediately released into the circulation after heparin administration. In addition to releasing H-TGL, heparin-like glycosaminoglycans have also been… (More)


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