Heparin-induced thrombocytopenia: an overview.

  title={Heparin-induced thrombocytopenia: an overview.},
  author={John G. Kelton},
  journal={Blood reviews},
  volume={16 1},
Heparin-induced thrombocytopenia (HIT) is the most important immunological drug reaction that patients face today. HIT typically develops in patients 5 days after starting heparin therapy, but can occur sooner with recent heparin exposure or rarely have a delayed onset. The platelet count typically drops below 150 x 10(9)/L (average 60 x 10(9)/L), and patients may experience a thrombotic episode simultaneously or shortly after the onset of thrombocytopenia. The thrombocytopenia and the… CONTINUE READING


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