Heparin-induced thrombocytopenia: a review of concepts regarding a dangerous adverse drug reaction.


Heparin is a natural agent with antithrombotic action, commercially available for therapeutic use as unfractionated heparin and low molecular weight heparin. Heparin-induced thrombocytopenia (HIT) is a serious adverse reaction to heparin that promotes antibody-mediated platelet activation. HIT is defined as a relative reduction in platelet count of 50… (More)
DOI: 10.1016/j.ramb.2012.11.004


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