Heparin crosslinked chitosan microspheres for the delivery of neural stem cells and growth factors for central nervous system repair.

@article{Skop2013HeparinCC,
  title={Heparin crosslinked chitosan microspheres for the delivery of neural stem cells and growth factors for central nervous system repair.},
  author={Nolan B Skop and Frances Calderon and Steven W Levison and Chirag D. Gandhi and Cheul Hyung Cho},
  journal={Acta biomaterialia},
  year={2013},
  volume={9 6},
  pages={6834-43}
}
An effective paradigm for transplanting large numbers of neural stem cells after central nervous system (CNS) injury has yet to be established. Biomaterial scaffolds have shown promise in cell transplantation and in regenerative medicine, but improved scaffolds are needed. In this study we designed and optimized multifunctional and biocompatible chitosan-based films and microspheres for the delivery of neural stem cells and growth factors for CNS injuries. The chitosan microspheres were… CONTINUE READING

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