Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats.

@article{Li2018HeparinPoloxamerTH,
  title={Heparin-Poloxamer Thermosensitive Hydrogel Loaded with bFGF and NGF Enhances Peripheral Nerve Regeneration in Diabetic Rats.},
  author={Rui Li and Yiyang Li and Yanqing Wu and Yingzheng Zhao and Huanwen Chen and Yuan Yuan and Ke Xu and Hongyu Zhang and Yingfeng Lu and Jian You Wang and Xiaokun Li and Xiaofeng Jia and Jian Xiao},
  journal={Biomaterials},
  year={2018},
  volume={168},
  pages={
          24-37
        }
}
Peripheral nerve injury (PNI) is a major burden to society with limited therapeutic options, and novel biomaterials have great potential for shifting the current paradigm of treatment. With a rising prevalence of chronic illnesses such as diabetes mellitus (DM), treatment of PNI is further complicated, and only few studies have proposed therapies suitable for peripheral nerve regeneration in DM. To provide a supportive environment to restore structure and/or function of nerves in DM, we… CONTINUE READING
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