Heparin-Calibrated Chromogenic Anti-Xa Activity Measurements in Patients Receiving Rivaroxaban: Can This Test Be Used to Quantify Drug Level?

@article{Gosselin2015HeparinCalibratedCA,
  title={Heparin-Calibrated Chromogenic Anti-Xa Activity Measurements in Patients Receiving Rivaroxaban: Can This Test Be Used to Quantify Drug Level?},
  author={Robert C Gosselin and Suzanne J Francart and Emily M. Hawes and Stephan Moll and William E. Dager and D M Adcock},
  journal={The Annals of pharmacotherapy},
  year={2015},
  volume={49 7},
  pages={777-83}
}
BACKGROUND Determination of plasma rivaroxaban concentration may be necessary in certain clinical situations. Rivaroxaban concentration can be accurately and rapidly determined using a chromogenic anti-activated factor X (factor Xa) assay with specific drug calibrator material. However, there are currently no Food and Drug Administration (FDA)-approved rivaroxaban calibrators available in the United States. OBJECTIVE To determine whether FDA-approved commercial kits for measuring heparin anti… CONTINUE READING
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