Heparin-Binding Protein (HBP): A Causative Marker and Potential Target for Heparin Treatment of Human Sepsis-Induced Acute Kidney Injury.

@article{Fisher2017HeparinBindingP,
  title={Heparin-Binding Protein (HBP): A Causative Marker and Potential Target for Heparin Treatment of Human Sepsis-Induced Acute Kidney Injury.},
  author={Jane L. Fisher and James A Russell and Peter Bentzer and Devyn Parsons and Stefano Secchia and Matthias M{\"o}rgelin and Keith R. Walley and John H. Boyd and Adam Linder},
  journal={Shock},
  year={2017},
  volume={48 3},
  pages={313-320}
}
RATIONALE Sepsis-induced acute kidney injury (AKI) is a common condition with high morbidity and mortality. Neutrophil-derived heparin-binding protein (HBP) induces vascular leakage and is a promising biomarker of sepsis-induced organ dysfunction. It remains unknown if HBP is prognostic of AKI in septic shock and if HBP could play a role in the… CONTINUE READING