Heparin/endothelial cell growth supplement regulates matrix gene expression and prolongs life span of vascular smooth muscle cells through modulation of interleukin-1

@article{Hsu1999HeparinendothelialCG,
  title={Heparin/endothelial cell growth supplement regulates matrix gene expression and prolongs life span of vascular smooth muscle cells through modulation of interleukin-1},
  author={J Hsu and Mei-Yu Hsu and Thomas Sorger and Meenhard Herlyn and Elliot M. Levine},
  journal={In Vitro Cellular & Developmental Biology - Animal},
  year={1999},
  volume={35},
  pages={647-654}
}
Vascular smooth muscle cells produce and respond to interleukin-1, a cytokine which modifies inflammation-associated vascular activities including the synthesis of extracellular matrix proteins. We have established vascular smooth muscle cells culture conditions in which heparin, in the presence of endothelial cell growth supplement, promotes cell… CONTINUE READING