Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats

Abstract

Heparanase, a mammalian endo-β-D-glucoronidase that specifically degrades heparan sulfate, has been implicated in inflammation and ischemic stroke. However, the role of heparanase in neuroinflammatory response in subarachnoid hemorrhage (SAH) has not yet been investigated. This study was designed to examine the association between heparanase expression and… (More)
DOI: 10.1186/s12974-017-0912-8

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