Heparan sulfate proteoglycans: structure, protein interactions and cell signaling.

  title={Heparan sulfate proteoglycans: structure, protein interactions and cell signaling.},
  author={Juliana Luporini Dreyfuss and Caio Vin{\'i}cius Saito Regatieri and Thais R Jarrouge and Renan Pelluzzi Cavalheiro and Lucia O. Sampaio and Helena B. Nader},
  journal={Anais da Academia Brasileira de Ciencias},
  volume={81 3},
Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular matrix in all the animal species. This review will focus on the structural characteristics of the heparan sulfate proteoglycans related to protein interactions leading to cell signaling. The heparan sulfate chains due to their vast structural diversity are able to bind and interact with a wide variety of proteins, such as growth factors, chemokines, morphogens, extracellular matrix components, enzymes… CONTINUE READING

From This Paper

Topics from this paper.
70 Citations
218 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 70 extracted citations


Publications referenced by this paper.
Showing 1-10 of 218 references

Similar Papers

Loading similar papers…