Heparan sulfate as a venostatic endothelial stabilizing factor.

@article{Hladovec1992HeparanSA,
  title={Heparan sulfate as a venostatic endothelial stabilizing factor.},
  author={J. Hladovec and F. Kornal{\'i}k},
  journal={Thrombosis research},
  year={1992},
  volume={68 6},
  pages={459-65}
}
A humoral transfer of a factor inducing a decrease of circulating endothelial cells (CEC) released during venostasis was demonstrated in rats. The possibility to block its activity by an in-vitro addition of protamine suggests its identity with an endogenous heparan sulfate possessing an inhibitory effect on endothelial turnover. This was supported by an… CONTINUE READING