Heparan sulfate: anchor for viral intruders?

  title={Heparan sulfate: anchor for viral intruders?},
  author={Dorothe Spillmann},
  volume={83 8},
Heparan sulfates (HS) are ubiquitous, polyanionic carbohydrate chains linked to core proteins in cell membranes and extracellular matrices of all eukaryotes. Due to the complex nature of the HS-biosynthesis, a wealth of different structures are produced. These seem to have a well defined distribution in different tissues and cells throughout development. Binding of endogenous proteins with different functional properties such as growth factors, adhesion molecules or enzymes, is one of the… CONTINUE READING

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