Hepadnaviral assembly is initiated by polymerase binding to the encapsidation signal in the viral RNA genome.

@article{Bartenschlager1992HepadnaviralAI,
  title={Hepadnaviral assembly is initiated by polymerase binding to the encapsidation signal in the viral RNA genome.},
  author={Ralf Bartenschlager and Heinz Schaller},
  journal={The EMBO journal},
  year={1992},
  volume={11 9},
  pages={3413-20}
}
Hepadnaviruses, as well as other pararetroviruses, express their pol (P) gene product unfused to the preceding core gene implying that these retroelements have developed a mechanism for initiating assembly and replication that is principally different from the one used by retroviruses and retrotransposons. We have analysed this mechanism for the human hepatitis B virus by using a newly developed, highly sensitive detection method based upon radiolabelling of the P protein at newly introduced… CONTINUE READING

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