Hepadna virus nucleocapsid and surface antigens and the antigen-specific antibodies associated with hepatocyte plasma membranes in experimental woodchuck acute hepatitis.

@article{Michalak1990HepadnaVN,
  title={Hepadna virus nucleocapsid and surface antigens and the antigen-specific antibodies associated with hepatocyte plasma membranes in experimental woodchuck acute hepatitis.},
  author={Tomasz I. Michalak and Bor-yaw Lin and Norma D. Churchill and P Dzwonkowski and J R Desousa},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1990},
  volume={62 6},
  pages={680-9}
}
Hepatocyte plasma membranes purified from five woodchucks with distinct serologic and histologic patterns of experimentally induced acute woodchuck hepatitis virus (WHV) infection were studied to determine the virus antigens expression and anti-viral specificity of the bound immunoglobulins. WHV core, e, and surface antigens (WHcAg, WHeAg, and WHsAg, respectively) were analyzed with the use of immunoblotting technique both in the native form of these membranes and in the membranes treated with… CONTINUE READING