Henoch-Schönlein nephritis: prognostic features and the challenge of therapy.

  title={Henoch-Sch{\"o}nlein nephritis: prognostic features and the challenge of therapy.},
  author={Howard Austin and James E. Balow},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  volume={2 5},
Henoch-Schönlein purpura is an intriguing entity of uncertain etiology associated with circulating IaA immune complexes, enhanced spontaneous immunoglobulin production, and an apparent imbalance in T cell regulatory functions. The associated glomerulonephritis is highly variable in nature and may profoundly influence clinical outcome. Prognostic features are reviewed in an effort to identify high-risk patients. Age, non-renal manifestations, non-selectivity of proteinuria, and evidence of… CONTINUE READING
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