Hendra and Nipah viruses: different and dangerous

@article{Eaton2006HendraAN,
  title={Hendra and Nipah viruses: different and dangerous},
  author={Bryan T. Eaton and Christopher C. Broder and Deborah J Middleton and Lin‐Fa Wang},
  journal={Nature Reviews. Microbiology},
  year={2006},
  volume={4},
  pages={23 - 35}
}
Hendra virus and Nipah virus are highly pathogenic paramyxoviruses that have recently emerged from flying foxes to cause serious disease outbreaks in humans and livestock in Australia, Malaysia, Singapore and Bangladesh. Their unique genetic constitution, high virulence and wide host range set them apart from other paramyxoviruses. These features led to their classification into the new genus Henipavirus within the family Paramyxoviridae and to their designation as Biosafety Level 4 pathogens… 
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Hendra and Nipah viruses: why are they so deadly?
Immunization strategies against henipaviruses.
Hendra virus and Nipah virus are recently discovered and closely related emerging viruses that now comprise the genus henipavirus within the sub-family Paramyxoviridae and are distinguished by their…
Henipaviruses are not yet history
ABSTRACT  Within the Paramyxoviridae family, Henipaviruses are the deadliest human pathogens. Nipah and Hendra viruses comprise the genus Henipavirus, zoonotic pathogens which cause encephalitis and…
HENDRA AND NIPAH VIRUS DISEASES SUMMARY
  • Medicine
  • 2008
Hendra virus (HeV) and Nipah virus (NiV) emerged in the last decade of the twentieth century as the causes of outbreaks of respiratory and neurological disease that infected a number of animal…
Hendra and Nipah infection: emerging paramyxoviruses.
Recent challenges in understanding Henipavirus immunopathogenesis: role of nonstructural viral proteins
TLDR
Hendra virus (HeV) and Nipah virus (NiV) are closely related recently emerged zoonotic paramyxoviruses, belonging to Henipavirus genus, considered as a potential agent for bioterrorism and classified as biosecurity level 4 pathogens.
Nipah viruses from Malaysia and Bangladesh: two of a kind?
TLDR
Comparisons of Nipah virus isolates in vitro have demonstrated differences in regulation of innate immunity and replicative ability, but similarities in infection outcomes and tissue tropism in the ferret model indicate that differences between viral isolates may not be the pivotal determinants of NIPah virus transmission.
HENDRA AND NIPAH VIRUS DISEASES
  • Medicine
  • 2010
Hendra virus (HeV) and Nipah virus (NiV) emerged in the last decade of the twentieth century as the causes of outbreaks of respiratory and neurological disease that infected a number of animal…
Henipavirus outbreaks to antivirals: the current status of potential therapeutics.
  • C. Broder
  • Biology
    Current opinion in virology
  • 2012
Hendra and Nipah Viruses: Lethal Zoonotic Paramyxoviruses
TLDR
This chapter focuses on Henipavirus biology, and the development of recombinant subunit immunogens would also represent a viable approach for vaccine development because they are inherently safe and are administered without risk of infection.
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