Hemozoin Biocrystallization in Plasmodium falciparum and the antimalarial activity of crystallization inhibitors

  title={Hemozoin Biocrystallization in Plasmodium falciparum and the antimalarial activity of crystallization inhibitors},
  author={Ernst Hempelmann},
  journal={Parasitology Research},
  • E. Hempelmann
  • Published 24 January 2007
  • Medicine
  • Parasitology Research
Quinine extracted from the bark of the South American Cinchona spp tree was the first of all antimalarials in western medicine and had been used since the 17th century. For more than 300 years, quinine was the only specific treatment for malaria. It was synthesized in 1944 (Woodward and Doering 1945) and has again become the antimalarial drug of choice in some parts of the world, both for uncomplicated and complicated forms of the disease and as monotherapy or as the backbone of combination… 
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