Hemostatic disturbances in patients with systemic inflammatory response syndrome (SIRS) and associated acute renal failure (ARF).

@article{GarcaFernndez2000HemostaticDI,
  title={Hemostatic disturbances in patients with systemic inflammatory response syndrome (SIRS) and associated acute renal failure (ARF).},
  author={Nuria Garc{\'i}a-Fern{\'a}ndez and R. Perez Montes and Andr{\'e}s Purroy and Eduardo Rocha},
  journal={Thrombosis research},
  year={2000},
  volume={100 1},
  pages={19-25}
}
Endothelial damage plays a central role in the development of an SIRS-related Multiple Organ Dysfunction Syndrome (MODS) as a consequence of the establishment of a hemostatic imbalance between coagulation and fibrinolysis systems. Until now, sepsis is the SIRS model that has been most studied. The aim of this study was to assess the endothelial damage and the hemostatic imbalance in early stages of an SIRS of different origins, and to study if there are any differences in these disturbances… CONTINUE READING