Hemostatic Resuscitation

  title={Hemostatic Resuscitation},
  author={Andrew P Cap and Jennifer M. Gurney and Michael Adam Meledeo},
  journal={Damage Control Resuscitation},



Blood Transfusion from the Military’s Standpoint: Making Last Century’s Standard Possible Today

Transfusion is an essential capability and saves lives on the battlefield and lessons learned in previous wars regarding the value of whole blood transfusion should be codified into military and civilian surgical practices.

The Acute Inflammatory Response in Trauma /Hemorrhage and Traumatic Brain Injury: Current State and Emerging Prospects

Novel approaches, including those from the field of systems biology, may yield therapeutic breakthroughs in T/HS and TBI in the near future.

PAS or plasma for storage of platelets? A concise review.

Recovery and survival after transfusion, as well as corrected count increments, are at least as good for platelets in PAS as for plasma, and recent data suggest they may even be better.

The use of whole blood in US military operations in Iraq, Syria, and Afghanistan since the introduction of low‐titer Type O whole blood: feasibility, acceptability, challenges

This study assessed the utilization patterns of LTOWB compared to warm fresh whole blood (WFWB) and blood component therapy (CT) in US Military Operations in Iraq/Syria and Afghanistan known as Operation Inherent Resolve (OIR) and Operation Freedom's Sentinel (OFS) respectively.

Blood clotting and traumatic injury with shock mediates complement‐dependent neutrophil priming for extracellular ROS, ROS‐dependent organ injury and coagulopathy

It is demonstrated that trauma‐shock and coagulation primes PMN for predominantly extracellular ROS production in a C5a‐dependent manner that contributes to endothelial barrier loss and organ injury, and potentially enhances traumatic coagulopathy.

Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock

In injured patients at risk for hemorrhagic shock, the prehospital administration of thawed plasma was safe and resulted in lower 30‐day mortality and a lower median prothrombin‐time ratio than standard‐care resuscitation.

Activated protein C plays no major roles in the inhibition of coagulation or increased fibrinolysis in acute coagulopathy of trauma-shock: a systematic review

None of the studies showed direct cause and effect relationships between activated protein C and the suppression of coagulation and increased fibrinolysis and no definitive diagnostic criteria or unified terminology have been established for ACOTS based on the activatedprotein C dynamics.

Blunt liver trauma: a descriptive analysis from a level I trauma center

In this retrospective analysis of liver injury experience in a level 1 trauma center, low grade liver injury in young males prevails and NOM is successful even for high graded injuries.

TEG Lysis Shutdown Represents Coagulopathy in Bleeding Trauma Patients: Analysis of the PROPPR Cohort

Low TEG LY30 does not reflect shutdown of enzymatic fibrinolysis with hypercoagulability, but rather a coagulopathic state of moderate fibrinogen consumption and platelet dysfunction that is associated with poor outcomes.