Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis: role in pulmonary inflammation following LPS

@inproceedings{Yang2016HemorrhagicSP,
  title={Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis: role in pulmonary inflammation following LPS},
  author={Jie Yang and Yanfeng Zhao and Peng Zhang and Yuehua Li and Yong Huan Yang and Yang Yang and Junjie Zhu and Xiao Song and Gening Jiang and Jie Fan},
  booktitle={Cell Death and Disease},
  year={2016}
}
Hemorrhagic shock (HS) often renders patients more susceptible to lung injury by priming for an exaggerated response to a second infectious stimulus. Acute lung injury (ALI) is a major component of multiple organ dysfunction syndrome following HS and regularly serves as a major cause of patient mortality. The lung vascular endothelium is an active organ that has a central role in the development of ALI through synthesizing and releasing of a number of inflammatory mediators. Cell pyroptosis is… CONTINUE READING

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