Hemorrhagic shock abolishes the myelopoietic response to turpentine-induced soft tissue injury.

@article{Raff1995HemorrhagicSA,
  title={Hemorrhagic shock abolishes the myelopoietic response to turpentine-induced soft tissue injury.},
  author={Gerhard Raff and David H. Livingston and Mei Ti Wang and Pranela Rameshwar},
  journal={The Journal of surgical research},
  year={1995},
  volume={59 1},
  pages={
          75-9
        }
}
Hemorrhagic shock has been shown to alter bone marrow (BM) myelopoiesis. Isolated hemorrhagic shock is uncommon after trauma and the combined effect of tissue injury and shock on myelopoiesis is unknown. We studied the growth of BM granulocyte-macrophage colony forming units (CFU-GM) following shock and soft tissue injury. Rats were anesthetized and allocated into one of four groups: CONTROL, sham neck dissection; SHOCK, rats were bled to a mean BP of 45 mmHG for 45 min and resuscitated with… CONTINUE READING
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