Hemorheology in Surgery—A Review

@article{Mller1987HemorheologyIS,
  title={Hemorheology in Surgery—A Review},
  author={R. M{\"u}ller and P. Mu{\vs}iki{\'c}},
  journal={Angiology},
  year={1987},
  volume={38},
  pages={581 - 592}
}
The rheological behavior of blood and its components under physiologic and pathophysiologic conditions is reviewed, with a focus on the type and extent of pathohemorheological changes in surgical patients during hospitalization and thereafter, as well as their clinical consequences with regard to thromboembolic complications. During the operation and the postoperative period various hemorheological and hemostasiological alterations acquire clinical signifcance: 1. hyperreagibility of platelets… 
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References

SHOWING 1-10 OF 51 REFERENCES
On the Therapy of Disturbances of Blood Fluidity
TLDR
The presented data of the multifunctional pharmacological properties of pentoxifylline on blood components and vessel wall suggest this drug as indicated for the treatment of the disorders of blood fluidity linked with many diseases.
Effects of major abdominal operations on human blood rheology.
TLDR
The results of this investigation suggest that abnormal rheological properties of blood and plasma should be considered in therapeutic attempts to improve microcirculatory flow and oxygen delivery to tissues.
Rheological and Anticoagulant Therapy of Patients with Chronic Peripheral Occlusive Arterial Disease (COAD)
TLDR
The combined therapy with anticoagulants and pentoxifylline had a marked therapeutic and probably prophylactic effect as regards thromboembolic complications in patients with COAD and other localizations of atherosclerosis.
Prevention of Post-Operative Thrombosis in Peripheral Arteriopathies. Pentoxifylline vs. Conventional Antiaggregants: A Six-Month Randomized Follow-up Study
TLDR
Patency and tolerability rate were significantly superior in those patients treated with pentoxifylline, suggesting that the combination of haemorheological effects with antihaemostaseological and antithrombotic properties offered by pentoxifyinglline may be of benefit in the prevention of reocclusion after vascular surgery.
Hemorheology and peripheral vascular diseases: a new therapeutic approach.
TLDR
Trental (pentoxifylline) largely satisfies the complex requirements of a hemorheologically active therapeutic agent in relation to peripheral vascular disease.
Shunt Thrombosis Prevention in Hemodialysis Patients — A Double-Blind, Randomized Study: Pentoxifylline vs Placebo
TLDR
Findings indicate that pentoxifylline medication markedly reduced the incidence of thrombosis of arteriovenous shunt and distinctly extended the shunt survival period, suggesting an effective antithrombotic property of the drug.
Prevention of Reocclusion After Prosthetic Bypass Operations in the Femoro-Popliteal Region: A Comparative Study of Pentoxifylline Versus Acetylsalicylic Acid
TLDR
Effectiveness of prevention of reocclusion was assessed by patency rates and drug tolerability and a significantly superior tolerability was found in the patients treated with pentoxifylline, 6 patients reporting adverse reactions as compared with 33 in the ASA-treated group.
The diagnosis of deep vein thrombosis using the 125 I fibrinogen test.
TLDR
Advantages of the test include its inability to detect phlebothrombosis in the upper femoral and iliac regions, the possible risk of serum hepatitis, and the number of personnel required if a large number of patients are to be screened.
Microcirculatory actions of general anesthetics.
TLDR
Alterations in the microvasculature involve primarily changes in the diameters of arterioles and venules and these, combined with the associated changes in arterial pressure and cardiac output, are responsible for the changes in organ blood flow that occur during general anesthesia.
...
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