Hemophilia: treatment options in the twenty-first century.

@article{Mannucci2003HemophiliaTO,
  title={Hemophilia: treatment options in the twenty-first century.},
  author={Pier Mannuccio Mannucci},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2003},
  volume={1 7},
  pages={1349-55}
}
In the last three decades, hemophilia has moved from the status of a neglected and often fatal hereditary disorder to that of a fully defined group of molecular-pathological entities for which safe and effective treatment is available. Hemophilia is likely to be the first widespread severe genetic condition to be cured by gene therapy in the third millennium. In the socio-economic arena it remains a challenge to humanity to know that four-fifths of the world's hemophiliacs still receive no… CONTINUE READING

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