Hemophagocytic syndrome in renal transplant recipients: report of 17 cases and review of literature.

@article{Karras2004HemophagocyticSI,
  title={Hemophagocytic syndrome in renal transplant recipients: report of 17 cases and review of literature.},
  author={Alexandre Karras and Eric Thervet and C. Legendre},
  journal={Transplantation},
  year={2004},
  volume={77 2},
  pages={238-43}
}
BACKGROUND Hemophagocytic syndrome (HPS) combines febrile hepatosplenomegaly, pancytopenia, hypofibrinemia, and liver dysfunction. It is defined by bone marrow and organ infiltration by activated, nonmalignant macrophages phagocytizing blood cells. HPS is often caused by an infectious or neoplastic disease and has rarely been described in renal transplant recipients. METHODS We retrospectively analyzed 17 cases of HPS after cadaveric renal transplantation (13 men and 4 women, age 41+/-8 years… CONTINUE READING

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