Hemolytic uremic syndrome: pathogenesis and update of interventions

@article{Palermo2009HemolyticUS,
  title={Hemolytic uremic syndrome: pathogenesis and update of interventions},
  author={Marina Sandra Palermo and Ramon Alfonso Exeni and Gabriela C Fern{\'a}ndez},
  journal={Expert Review of Anti-infective Therapy},
  year={2009},
  volume={7},
  pages={697 - 707}
}
The typical form of hemolytic uremic syndrome (HUS) is the major complication of Shiga toxin-producing Escherichia coli infections. HUS is a critical health problem in Argentina since it is the main cause of acute renal failure in children and the second cause of chronic renal failure, accounting for 20% of renal transplants in children and adolescents in Argentina. Despite extensive research in the field, the mainstay of treatment for patients with HUS is supportive therapy, and there are no… 
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Specific actions at different levels of prevention of Hemolytic uremic syndrome associated with intestinal infection by Shiga toxin-producing bacteria are described.
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TLDR
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TLDR
The current knowledge about pathogenic mechanisms is presented and traditional and innovative therapeutic approaches are discussed, with special focus in national status and contributions made by Argentinean groups.
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TLDR
The differences in the epidemiology and presentation of E. coli pathogen meant a challenge for public health and scientific research to increase the knowledge of HUS‐pathophysiology and to improve available therapies to treat HUS.
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Antibody Response to Shiga Toxins in Argentinean Children with Enteropathic Hemolytic Uremic Syndrome at Acute and Long-Term Follow-Up Periods
TLDR
The simultaneous evaluation by the two methods allowed us to differentiate acute HUS patients from NHC with a great specificity and accuracy, in order to confirm the HUS etiology when pathogenic bacteria were not isolated from stools.
Hemolytic Uremic Syndrome as a Cause of Adult Acute Renal Failure / Eriskin Akut Bobrek Yetmezliginin Bir Sebebi Olarak Hemolitik Uremik Sendrom
TLDR
The clinical features, diagnosis, pathophysiology, and treatment of an adult with acute renal failure due to the thrombotic microangiopathy with hemolytic uremic syndrome are discussed.
Artículos de investigación científica Síndrome urémico hemolítico en Uruguay. Aspectos microbiológicos y clínicos, aportes para su conocimiento regional. Hemolytic uremic syndrome in Uruguay. Microbiological and clinical aspects, contributions to the regional knowledge.
TLDR
The characteristics of STEC strains recovered from children undergoing HUS are determined, and some clinical and epidemiological features of these cases are reported, in children whose households are located outside Montevideo capital city.
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TLDR
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