Hemolysate-filled polyethyleneimine and polyurea microcapsules as potential red blood cell substitutes: effect of aqueous monomer type on properties of the prepared microcapsules.

@article{ElGibaly2004HemolysatefilledPA,
  title={Hemolysate-filled polyethyleneimine and polyurea microcapsules as potential red blood cell substitutes: effect of aqueous monomer type on properties of the prepared microcapsules.},
  author={Ibrahim El-Gibaly and Mohammed Khaleel Anwar},
  journal={International journal of pharmaceutics},
  year={2004},
  volume={278 1},
  pages={
          25-40
        }
}
In this paper, we describe the synthesis and characterization of rabbit hemolysate-filled polyethyleneimine (PEI)- or polyurea (PU)-type artificial red blood cells (ARBCs) with different membrane compositions. These microcapsules were prepared by making use of the interfacial polymerization (IP) reaction between the water-soluble amine monomers (triethylamine (TEA), ethylene glycol-bis(beta-aminoethyl ether)-N,N'-tetraacetic acid (EGATA), diethylenetriamine (DETA), tetramethyl diaminomethane… CONTINUE READING