Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice

@inproceedings{Wu2017HemojuvelinRT,
  title={Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice},
  author={Qian Wu and Yuanyuan Shen and Yunlong Tao and Jiayu Wei and Hao Wang and Peng An and Zhuzhen Zhang and Hong Gao and Tianhua Zhou and Fudi Wang and Junxia Min},
  booktitle={Cell Discovery},
  year={2017}
}
Hereditary hemochromatosis and iron imbalance are associated with susceptibility to bacterial infection; however, the underlying mechanisms are poorly understood. Here, we performed in vivo bacterial infection screening using several mouse models of hemochromatosis, including Hfe (Hfe−/−), hemojuvelin (Hjv−/−), and macrophage-specific ferroportin-1 (Fpn1fl… CONTINUE READING