Hemoglobin level threshold for cardiac remodeling and quality of life in myelodysplastic syndrome.

@article{Oliva2005HemoglobinLT,
  title={Hemoglobin level threshold for cardiac remodeling and quality of life in myelodysplastic syndrome.},
  author={Esther Natalie Oliva and Borislav D. Dimitrov and Frank Antonio Benedetto and Arianna D'Angelo and Francesco Nobile},
  journal={Leukemia research},
  year={2005},
  volume={29 10},
  pages={1217-9}
}
Treatment of myelodysplastic syndrome (MDS) with epoietin is costly. However, cardiac morbidity associated with anemia has not been investigated in MDS. We studied this aspect in 39 patients. Echocardiography detected cardiac remodeling in 11 of 12 transfusion-dependent versus 13 of 27 transfusion-free patients (P=0.017). Hemoglobin independently indicated cardiac hypertrophy (P=0.004); each unit increase predicted a 49% reduction in the risk of remodeling confirmed by the area under the ROC… CONTINUE READING

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Kidney Disease: Improving Global Outcomes guidelines on anaemia management in chronic kidney disease: a European Renal Best Practice position statement.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 2013
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