Hemoglobin labeled by radioactive lysine; erythrocyte life cycle.


A dog, doubly depleted of blood cells and plasma proteins, was fed dl-lysine labeled with C(14) in the epsilon carbon position. In the first 8 hours 28 per cent of the administered C(14) was excreted in the urine; in the first 72 hours, 35 per cent. Twenty-four hours after feeding, 4.2 per cent of the fed C(14) was circulating in the plasma, decreasing to 1… (More)


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