Hemoglobin induces inflammation after preterm intraventricular hemorrhage by methemoglobin formation

@inproceedings{Gram2013HemoglobinII,
  title={Hemoglobin induces inflammation after preterm intraventricular hemorrhage by methemoglobin formation},
  author={Magnus Gram and Snj{\'o}laug Sveinsd{\'o}ttir and Karsten Ruscher and Stefan Rocco Hansson and Magnus Cinthio and Bo {\AA}kerstr{\"o}m and David Ley},
  booktitle={Journal of Neuroinflammation},
  year={2013}
}
BackgroundCerebral intraventricular hemorrhage (IVH) is a major cause of severe neurodevelopmental impairment in preterm infants. To date, no therapy is available that prevents infants from developing serious neurological disability following IVH. Thus, to develop treatment strategies for IVH, it is essential to characterize the initial sequence of molecular events that leads to brain damage. In this study, we investigated extracellular hemoglobin (Hb) as a causal initiator of inflammation in… CONTINUE READING
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