Hemoglobin desaturation: its occurrence during sleep in patients with cystic fibrosis.

@article{Francis1980HemoglobinDI,
  title={Hemoglobin desaturation: its occurrence during sleep in patients with cystic fibrosis.},
  author={Paul W. Francis and Nestor Luiz Muller and Dennis Gurwitz and Donald W. Milligan and Henry Levison and A. Charles Bryan},
  journal={American journal of diseases of children},
  year={1980},
  volume={134 8},
  pages={734-40}
}
Sleep studies were performed in 20 clinically stable cystic fibrosis (CF) patients (mean age, 18.2 years) to determine the magnitude of fall in hemoglobin saturation (Sao2) during sleep and to relate these changes to pulmonary function and echocardiographic findings. Five healthy young adults served as controls. In both groups, the maximum fall in Sao2 was seen during rapid eye movement (REM) sleep. The mean maximum fall in the control group during REM sleep was 2.0% (range, 1% to 3%), compared… CONTINUE READING
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