Hemoglobin as a source of iron overload in multiple sclerosis: does multiple sclerosis share risk factors with vascular disorders?

@article{Bamm2014HemoglobinAA,
  title={Hemoglobin as a source of iron overload in multiple sclerosis: does multiple sclerosis share risk factors with vascular disorders?},
  author={Vladimir Varlen Bamm and George Harauz},
  journal={Cellular and Molecular Life Sciences},
  year={2014},
  volume={71},
  pages={1789-1798}
}
Although iron is known to be essential for the normal development and health of the central nervous system, abnormal iron deposits are found in and around multiple sclerosis (MS) lesions that themselves are closely associated with the cerebral vasculature. However, the origin of this excess iron is unknown, and it is not clear whether this is one of the primary causative events in the pathogenesis of MS, or simply another consequence of the long-lasting inflammatory conditions. Here, applying a… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 19 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Source of iron overload in multiple sclerosis

Cellular and Molecular Life Sciences • 2014
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 136 references

How do immune cells support and shape the brain in health, disease, and aging?

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2013
View 5 Excerpts
Highly Influenced

Immunologic privilege in the central nervous system and the blood-brain barrier.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2013
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…