Hemogenic endothelium: a vessel for blood production.

  title={Hemogenic endothelium: a vessel for blood production.},
  author={Veronica I. Antas and Mohammad A. Al-Drees and Alexander J A Prudence and Daisuke Sugiyama and Stuart T Fraser},
  journal={The international journal of biochemistry & cell biology},
  volume={45 3},
Blood cell production, or hematopoiesis, is critical to the survival of the developing mammalian embryo. The origins of hematopoietic stem cells, capable of giving rise to all blood cell types, are being revealed. During embryogenesis, hematopoietic stem and progenitor cells are generated from a unique population of vascular endothelium termed hemogenic endothelial cells. These unusual endothelial cells are found in a restricted number of sites in the conceptus and within a narrow window of… CONTINUE READING


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throid / myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells

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