Hemodynamics and In-stent Restenosis: Micro-CT Images, Histology, and Computer Simulations

  title={Hemodynamics and In-stent Restenosis: Micro-CT Images, Histology, and Computer Simulations},
  author={Stefano Morlacchi and Brandis K Keller and Patrizia Arcangeli and Marta Balzan and Francesco Migliavacca and Gabriele Dubini and Julian Gunn and Nadine D. Arnold and Andrew J. Narracott and David Evans and Patricia Victoria Lawford},
  journal={Annals of Biomedical Engineering},
A model that combines the results of in vivo experiment, 3D image data, and computer simulation has been developed. Twelve identical stents were implanted into six healthy pigs and explanted at a range of different post-recovery periods from 6 h to 28 days. The stented vessel segments were embedded in methacrylate resin for the preparation of transverse histological sections and imaged using ultra-high resolution micro-CT. The resulting CT data was used to reconstruct the 3D geometry of the… CONTINUE READING


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Circumfer - ential vascular deformation after stent implantation alters wall shear stress evacuate with time - dependent 3 D computational fluid dynamics models

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