Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.

@article{Kawashima1989HemodynamicRT,
  title={Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.},
  author={Atsuhiro Kawashima and Keishi Kubo and Tsutomu Yoshimura Hiroyuki Kobayashi and Masahiro Sekiguchi},
  journal={Journal of applied physiology},
  year={1989},
  volume={67 5},
  pages={
          1982-9
        }
}
To verify the presence of the constitutional abnormality implicated in the pathogenesis of high-altitude pulmonary edema (HAPE), we evaluated the hemodynamic responses to hypoxia, hypobaria, and exercise in HAPE-susceptible subjects (HAPE-S). HAPE-S were five males with a history of HAPE. Five healthy volunteers who had repeated experiences of mountain climbing without any history of altitude-related problems served as controls. HAPE-S showed much greater increase in pulmonary vascular… CONTINUE READING
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