Hemodynamic effects of rapid vancomycin infusion in critically ill patients.

@article{Stier1990HemodynamicEO,
  title={Hemodynamic effects of rapid vancomycin infusion in critically ill patients.},
  author={G R Stier and Robb McGory and William D. Spotnitz and Karen J Schwenzer},
  journal={Anesthesia and analgesia},
  year={1990},
  volume={71 4},
  pages={394-9}
}
The rapid infusion of vancomycin produces histamine release resulting in rash ("red-man's" syndrome) and hypotension. Because this phenomenon has been described primarily in healthy subjects, we prospectively studied the rapid infusion of vancomycin in 16 critically ill patients after open heart surgery in an attempt to document histamine release with… CONTINUE READING