Hemodynamic effects of dobutamine after cardiopulmonary bypass in children.

@article{Bohn1980HemodynamicEO,
  title={Hemodynamic effects of dobutamine after cardiopulmonary bypass in children.},
  author={Desmond J Bohn and C S Poirier and J F Edmonds and Glenn A Barker},
  journal={Critical care medicine},
  year={1980},
  volume={8 7},
  pages={367-71}
}
The synthetic inotropic agent, dobutamine, has reportedly increased cardiac output in adults after cardiopulmonary bypass with minimal side effects. Its use in children, after surgical correction of congenital heart disease, was tested by infusing the drug at 1, 4, 7, and 10 micrograms/kg x min in 11 children. While significant increases in cardiac index above control (23, 23, and 16% at 4, 7, and 10 micrograms/kg x min, respectively) were observed, this was achieved at the expense of… CONTINUE READING