Hemodynamic effects of calcitonin gene-related peptide in spontaneously hypertensive rats.

@article{Ando1990HemodynamicEO,
  title={Hemodynamic effects of calcitonin gene-related peptide in spontaneously hypertensive rats.},
  author={K{\^o}ichi Ando and Barbara L. Pegram and Edward David Frohlich},
  journal={The American journal of physiology},
  year={1990},
  volume={258 2 Pt 2},
  pages={R425-9}
}
Systemic and regional hemodynamic effects of intravenously injected calcitonin gene-related peptide (CGRP), 220 and 650 pmol, were compared in nine Wistar-Kyoto (WKY) and nine spontaneously hypertensive rats (SHR). CGRP (higher dose) reduced mean arterial pressure (from 135 +/- 2 to 83 +/- 2 and from 179 +/- 4 to 116 +/- 3 mmHg; P less than 0.01, each, in WKY and SHR, respectively) through a fall (-38 +/- 4 and -40 +/- 3%; P less than 0.01) in total peripheral resistance associated with an… CONTINUE READING
9 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…