Hemodynamic and microcirculatory changes during development of renal hypertension.

@article{Hernndez1995HemodynamicAM,
  title={Hemodynamic and microcirculatory changes during development of renal hypertension.},
  author={Isabel Hern{\'a}ndez and Andrew S. Greene},
  journal={The American journal of physiology},
  year={1995},
  volume={268 1 Pt 2},
  pages={H33-8}
}
To study the progression of vessel loss (rarefaction) during the development of hypertension, a plastic window was chronically implanted over the biceps femoralis muscle of reduced renal mass (RRM) and sham-operated control (SOC) rats on a low-salt diet (0.4%). Blood pressure was measured directly via a catheter implanted in the femoral artery, and tissue blood flow was measured by laser-Doppler flowmetry before and after local topical application of sodium nitroprusside. Measurements were made… CONTINUE READING