Hemodynamic and metabolic response after abrupt uithdrawal of long-term propranolol.


Because the mechanism of adverse reactions to abrupt withdrawal of propranolol in patients with coronary disease is an enigma, we studied the effect of cessation of propranolol on beta receptor reactivity to catecholamine stimulation. Heart rate and maximum rate of rise of left ventricular pressur (dP/dt max) during isoproterenol infusions and plasma free… (More)