Hemodynamic and inotropic effects of nitric oxide in pulmonary hypertension.

  title={Hemodynamic and inotropic effects of nitric oxide in pulmonary hypertension.},
  author={Edward P. Chen and Hartmuth B. Bittner and Robert Duane Davis and P Van Trigt},
  journal={The Journal of surgical research},
  volume={69 2},
Right ventricular failure following cardiac transplantation is most commonly related to pre-existent recipient pulmonary hypertension secondary to chronic congestive heart failure. Although nitric oxide has had some role clinically in improving pulmonary hemodynamics and right ventricular function in this setting, an appropriate large-animal model of stable pulmonary hypertension has not been available for basic investigation of this problem. This study was designed to examine the hemodynamic… CONTINUE READING