Hemodynamic and excretory response of the neonatal canine kidney to acute volume expansion.

@article{Goldsmith1979HemodynamicAE,
  title={Hemodynamic and excretory response of the neonatal canine kidney to acute volume expansion.},
  author={David I. Goldsmith and Alfred Drukker and M. Donald Blaufox and Chester M. Edelmann and Adrian Spitzer},
  journal={The American journal of physiology},
  year={1979},
  volume={237 5},
  pages={F392-7}
}
It is generally recognized that developing animals retain sodium due to an enhanced reabsorption in distal tubule segements, even when the amount administered is in excess of their needs. This study was designed to test the relationship between this relative inability to dispose of a saline load and the functional characteristics of the kidney during postnatal maturation. In addition, we explored the role played by some of the factors known to affect natriuresis in the adult subject… CONTINUE READING