Hemodynamic and electrophysiologic effects of low osmolar contrast agents during coronary angiography in the dog and the rabbit.


The electrophysiological tolerability of ioxaglate (160 mgI/ml) and iohexol (140 mgI/ml) was assessed in rabbits (n = 12 per group). There was a significant induction of ventricular fibrillation in the group given iohexol. An explanation for this phenomenon could be the lack of sodium in this preparation. Ioxaglate, iopamidol and iohexol (all at 320 mgI/ml… (More)


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