Hemodialysis in the treatment of lactic acidosis in diabetics treated by metformin: a study of metformin elimination.

@article{Lalau1989HemodialysisIT,
  title={Hemodialysis in the treatment of lactic acidosis in diabetics treated by metformin: a study of metformin elimination.},
  author={Jean-Daniel Lalau and Michel M. Andrejak and Philippe Morini{\`e}re and Bruno Coevoet and Xavier Debussche and Pierre François Westeel and Aur{\'e}lien Fournier and Jean Quichaud},
  journal={International journal of clinical pharmacology, therapy, and toxicology},
  year={1989},
  volume={27 6},
  pages={
          285-8
        }
}
The aim of this study was to determine the characteristics of metformin elimination by dialysis. For this purpose we report the kinetic parameters during dialysis and the metformin clearance (i.e. dialysance) in four patients presenting with lactic acidosis which occurred on metformin therapy. We also studied metformin elimination in two chronically hemodialyzed diabetic patients inadvertently maintained on metformin therapy and in two chronically hemodialyzed non-diabetic patients who took a… CONTINUE READING

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VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

[Metformin associates lactic acidosis].

  • Presse medicale
  • 2012
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Lactic Acidosis in a Patient with Type 2 Diabetes Mellitus.

  • Clinical journal of the American Society of Nephrology : CJASN
  • 2015
VIEW 13 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Toxicokinetics of Metformin During Hemodialysis

Paul Ayoub, P O Hétu, +5 authors Marc Ghannoum
  • Kidney international reports
  • 2017

Pharmacokinetics of Metformin in Patients Receiving Regular Hemodiafiltration.

  • American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2016
VIEW 1 EXCERPT

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