Hemodialysis impairs endothelial function via oxidative stress: effects of vitamin E-coated dialyzer.

@article{Miyazaki2000HemodialysisIE,
  title={Hemodialysis impairs endothelial function via oxidative stress: effects of vitamin E-coated dialyzer.},
  author={Hiromi Miyazaki and Hiroshi Matsuoka and Hiroyuki Itabe and Makoto Akishima Usui and Shinichiro Ueda and Shinichi Okuda and Toshinobu Imaizumi},
  journal={Circulation},
  year={2000},
  volume={101 9},
  pages={
          1002-6
        }
}
BACKGROUND Patients who undergo hemodialysis experience accelerated atherosclerosis and premature death. Recent evidence suggests that endothelial dysfunction proceeds to and exacerbates atherosclerosis. It remains unknown whether hemodialysis per se causes endothelial dysfunction. METHODS AND RESULTS We evaluated endothelial function estimated by flow-mediated vasodilation during reactive hyperemia using high-resolution ultrasound Doppler echocardiography before and after a single session in… CONTINUE READING

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