Hemocompatibility evaluation of poly(glycerol-sebacate) in vitro for vascular tissue engineering.

@article{Motlagh2006HemocompatibilityEO,
  title={Hemocompatibility evaluation of poly(glycerol-sebacate) in vitro for vascular tissue engineering.},
  author={Delara Motlagh and Jing Yang and Karen Y Lui and Antonio R. Webb and Guillermo A Ameer},
  journal={Biomaterials},
  year={2006},
  volume={27 24},
  pages={4315-24}
}
Poly(glycerol-sebacate) (PGS) is an elastomeric biodegradable polyester that could potentially be used to engineer blood vessels in vivo. However, its blood-material interactions are unknown. The objectives of this study were to: (a) fabricate PGS-based biphasic tubular scaffolds and (b) assess the blood compatibility of PGS in vitro in order to get some insight into its potential use in vivo. PGS was incorporated into biphasic scaffolds by dip-coating glass rods with PGS pre-polymer. The… CONTINUE READING