Hemin or butyrate increases constitutive erythropoietin formation by mouse erythroleukemia cell lines.

Abstract

The murine erythroleukemic cell lines NN10 and IW32 secrete erythropoietin (Epo) constitutively. Although both cell lines have Epo receptors (Epo-R), they do not respond to external Epo to undergo erythroid differentiation. In both cell lines, hemoglobin synthesis can be induced by hemin or butyrate. We report here on the effects of these two inducers on… (More)

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Cite this paper

@article{Hermine1993HeminOB, title={Hemin or butyrate increases constitutive erythropoietin formation by mouse erythroleukemia cell lines.}, author={Olivier Hermine and Yanmei Dong and Nega Beru and Eugene Goldwasser}, journal={Experimental hematology}, year={1993}, volume={21 9}, pages={1207-11} }