Hemimegalencephaly: part 1. Genetic, clinical, and imaging aspects.

  title={Hemimegalencephaly: part 1. Genetic, clinical, and imaging aspects.},
  author={Laura Flores-Sarnat},
  journal={Journal of child neurology},
  volume={17 5},
  pages={373-84; discussion 384}
Hemimegalencephaly is a rare hamartomatous malformation of the brain, remarkable for its extreme asymmetry. It can be isolated or associated with several neurocutaneous syndromes; less frequently, it also involves the brain stem and cerebellum. Traditionally, hemimegalencephaly has been considered a primary neuroblast migratory disturbance. At present, genetic theories of pathogenesis and modern histopathology provide a basis for this complex malformation as a primary disturbance in cellular… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 65 extracted citations

Similar Papers

Loading similar papers…