Corpus ID: 53686818

Hemifacial Spasm : Evaluation and Management , with Emphasis on Botulinum Toxin Therapy

@inproceedings{Borodic2011HemifacialS,
  title={Hemifacial Spasm : Evaluation and Management , with Emphasis on Botulinum Toxin Therapy},
  author={G. Borodic},
  year={2011}
}
Hemifacial spasm is a disorder of the facial nerve characterized by involuntary synkinetic movement of facial muscles on the afflicted side associated with minimal facial weakness. Management of this disorder has transcended several medical and surgical specialties. The condition has implications for ophthalmological practice because of visual obstruction produced by involuntary eyelid closure, which is most troublesome to patients. Neuroophthalmic or neurological evaluation is necessary for… Expand
1 Citations
Disorders of Involuntary Facial Movement and Blepharospasm , Contemporary Evaluation and Management
Prior to considering the subject of involuntary facial movement conditions, such as blepharospasm, it is useful to first define disease descriptive terms. Benign essential blepharospasm refers toExpand

References

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Botulinum A Toxin for Treatment of Aberrant Facial Nerve Regeneration
TLDR
Dose requirements to treat aberrant regeneration of the facial nerve were substantially less than needed to treat blepharospasm and Meige syndrome and dose comparisons were made with 269 injections in 71 patients with hemifacial spasm. Expand
[Hemifacial spasm treated with botulinum toxin].
TLDR
The most frequent side-effect was a ptosis which was observed in 1 out of 6 injections and was due to diffusion of the botulinum toxin over a territory larger than expected. Expand
Contralateral Injections of Botulinum A Toxin for the Treatment of Hemifacial Spasm to Achieve Increased Facial Symmetry
TLDR
Six patients noted facial asymmetry after botulinum toxin injection for hemifacial spasm and five of the six patients desired this approach with subsequent injections. Expand
Botulinum A Toxin for (Expressionistic) Ptosis Overcorrection After Frontalis Sling
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TLDR
Botulinum A toxin was injected into the frontalis muscle in two patients with complete third nerve palsies to limit intermittent upper lid retraction after a frontalis sling procedure, representing a clinical example of a denervation field produced by a point injection of botulinum toxin. Expand
Effect of treatment with botulinum toxin on neurogenic blepharospasm.
TLDR
Thirty four patients with blepharospasm, of whom 28 also had the oromandibular dystonia syndrome, were treated with injections of botulinum toxin type A into the orbicularis oculi, and 28 showed functional improvement after the treatment. Expand
Botulinum a toxin for the treatment of spasmodic torticollis: Dysphagia and regional toxin spread
TLDR
Limiting the dose administered to the sternomastoid to 100 IU, substantially reduced the incidence of dysphagia and suggested that the quantity of toxin injected into the sterno-cervical muscle was related to the quality of the toxin. Expand
Long-term results and complications of botulinum A toxin in the treatment of blepharospasm.
TLDR
There was no clear relationship between toxin dose and the amount of spasm reduction or duration of response, and average duration of beneficial effect remained constant from the first through the twelfth injections. Expand
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TLDR
It is concluded that the normal facial nerve is vulnerable to minor compression, the primary pathophysiologic mechanism in hemifacial spasm is ectopic/ephaptic excitation due to compression and demyelination of the intracranial segment of the facial nerve. Expand
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TLDR
Histologic evaluation was conducted on 12 orbicularis oculi specimens from 11 patients with essential blepharospasm and Meige's disease who had received an average of 11.3 injections of botulinum A toxin over 3.5 years, finding Repeated injections ofBotulinum toxin into human muscle do not appear to cause irreversible muscle atrophy or other degenerative changes. Expand
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TLDR
Thirty-nine patients with blepharospasm were treated with injections of botulinum A toxin into the lid and brow, finding that tearing, dry-eye symptoms, or transient ptosis occurred in 20% of injections, especially in patients who had had previous eyelid surgery. Expand
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