Hemidesmosome Formation Is Initiated by the β4 Integrin Subunit, Requires Complex Formation of β4 and HD1/Plectin, and Involves a Direct Interaction between β4 and the Bullous Pemphigoid Antigen 180

Abstract

Hemidesmosomes (HDs) are stable anchoring structures that mediate the link between the intermediate filament cytoskeleton and the cell substratum. We investigated the contribution of various segments of the b 4 integrin cytoplasmic domain in the formation of HDs in transient transfection studies using immortalized keratinocytes derived from an epidermolysis… (More)

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@article{Schaapveld1998HemidesmosomeFI, title={Hemidesmosome Formation Is Initiated by the β4 Integrin Subunit, Requires Complex Formation of β4 and HD1/Plectin, and Involves a Direct Interaction between β4 and the Bullous Pemphigoid Antigen 180 }, author={Roel Q J Schaapveld and Luca Borradori and Dirk Geerts and Manuel R. van Leusden and Ingrid Kuikman and Mirjam G. Nievers and Carien M. Niessen and Renske D. M. Steenbergen and Peter J. F. Snijders and Arnoud Sonnenberg}, journal={The Journal of Cell Biology}, year={1998}, volume={142}, pages={271 - 284} }